Each life insurance company has their own set of underwriting guidelines and classes of risk they will accept based on several factors including family history.
Usually life insurance companies are concerned with health history of your parents / grandparents, and any history of cancer, heart disease, or other health conditions requiring medication, or those which may reduce your life expectancy.
In addition, your personal health history and current health is important, as well as any medication you may be taking, or have taken in the past for a health problem.
There are many insurers which specialize in insuring people with high risk medical conditions. Also, there are insurers which offer
life insurance no medical exams policies, and no medical question life insurance for people who have been declined, are having problems getting life insurance, or just don't want to take a physical exam.